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As seen in: Nature, Gut Journal, Genome Biology, Science Magazine, BioRxiv, Cell Press, The Lancet, EMBL
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Articles

Unbinned contigs expand known diversity in the global microbiome

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By Vishnu PK, Oleksandr M. Maistrenko, Anthony Fullam, Daniel R. Mende, Ece Kartal, Luis Pedro Coelho, Anja Spang, Peer Bork, Thomas Schmidt
| Nature Verified
Abstract The ongoing census of microbial life is hampered by disparate sampling across Earth’s habitats, challenges in isolating uncultivated organisms, limited resolution in taxonomic marker gene amplicons and incomplete recovery of metagenome-assembled genomes. Here we quantify discoverable Bacterial and Archaeal diversity in a comprehensive, curated cross-habitat dataset of 92,187 publicly available metagenomes.
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A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases - Nature Communications

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By Kanta Chechi, Rima Chakaroun, Antonis Myridakis, Sofia K. Forslund-Startceva, Sebastién Fromentin, Trine Nielsen, Eugeni Belda, Edi Prifti, Pierre Bel Lassen, Gwen Falony, Sara Vieira-Silva, Julien Chilloux, Kazuhiro Sonomura, Lesley Hoyles, Laura Martinez-Gili, Francesco Pallotti, Petros Andrikopoulos, Francesc Puig-Castellví, Ines Y. Castro-Dionicio, Hugo Roume, Nicolas Pons, Emmanuelle Le Chatelier, Benoit Quinquis, Magali Berland, Michael T. Olanipekun, Matthias Blüher, Luis Pedro Coelho, Kevin Da Silva, Pilar Galan, Boyang Ji, Ana Neves, Christine Rouault, Joe-Elie Salem, Valentina Tremaroli, Tue H. Hansen, Nadja B. Søndertoft, Helle Pedersen, Peter Mark, Jens P Goetze, Lars Køber, Henrik Vestergaard, Torben Frøstrup Hansen, Jean-Daniel Zucker, Serge Hercberg, Fredrik Bäckhed, Ivica Letunic, Jean-Michel Oppert, Jens Christian Nielsen, Jeroen Raes, Ioanna Tzoulaki, Abbas Dehghan, Verena Zuber, Emmanuelle Bouzigon, Mark Lathrop, Parminder Raina, Philippe Froguel, Fumihiko Matsuda, Florence Demenais, Dominique Gauguier, Michael Stumvoll, Peer Bork, Oluf Borbye Pedersen, S. Ehrlich, Karine Clément, Marc-Emmanuel Dumas, Judith Aron-Wisneswky, Romina Pacheco Tapia, Nathalie Galleron, Manyi Jia, Angelos Manolias, Bridget Holmes, Solia Adriouch, Christian Lewinter, Taka-Aki Sato
| Nature Verified
Abstract Cardiovascular diseases (CVD) remain a major global health challenge. Early markers of disease initiation and progression are urgently needed. We, and others, have previously shown changes in the gut microbiome in association with metabolic and CVD. Here, we demonstrate that gut microbiome-related changes can be detected in association with subclinical variations in heart and kidney function.
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Planetary microbiome structure and generalist-driven gene flow across disparate habitats

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By Chan Kim, Daniel Podlesny, Supriya Khedkar, Anthony Fullam, Askarbek Orakov, Christian Schudoma, Anastasiia Grekova, Michael Kuhn, Peer Bork, Jonas Schiller, Jonas Schiller, Shahriyar Mahdi Robbani, Shahriyar Mahdi Robbani
| Cell Press Verified
Due to their adaptability to diverse environmental conditions and resources, generalist microbes thrive across a broad range of habitats. Through dispersal, generalists can transport both their own genetic material and horizontally acquired genes from sympatric species into new habitats (Figure 5A).
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