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Peter Martin

As seen in: MSN, Color Research & Application, Nature, Wiley, Wiley Online Library, Yahoo News, Yahoo News New Zealand, Memory Studies, BMJ Open, BMJ Quality & Safety and
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Articles

BRG1-mediated suppression of ferroptosis underlies BTK inhibitor resistance

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By Soo-Yeon Hwang, Xiangao Huang, Belem Yoval-Sánchez, Peter Martin, Caitlin Gribbin, Preetesh Jain, Michael Wang, Lalit Sehgal, Robert A Baiocchi, Inah Hwang, Alexander Galkin, Hojoong Kwak, Lapo Alinari, Selina Chen-Kiang, Jihye Paik, Helgi Nikolli, Sieun Yang, Jeongbin Heo, Maurizio DiLiberto, Hongwu Zheng
| Nature Verified
Abstract Resistance to Bruton’s tyrosine kinase inhibitors (BTKi) remains a major therapeutic challenge in B-cell malignancies. Here, we identify chromatin remodeler BRG1-mediated suppression of ferroptosis as a central mechanism of BTKi resistance in mantle cell lymphoma (MCL), in which aberrant BRG1-dependent transcription program protects cells from BTKi-induced ferroptosis by restricting reactive oxygen species (ROS) and labile iron.
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Trump’s Libya push aims to turn a fragile truce into an oil bonanza

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By Peter Martin, Paul Burkhardt Verified
| MSN Verified
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Microsoft Cares About Your Privacy US Army identifies soldier found dead during Morocco exercise

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By Peter Martin
| MSN Verified
(Bloomberg) -- The body of one of two US Army service members who went missing in Morocco during a military exercise has been recovered and identified, the US Army said . A Moroccan military search team found First Lieutenant Kendrick Lamont Key Jr. in the water along the shoreline near the Cap Draa Training Area on May 9, the US Army said in a press release on Sunday. Search and rescue operations continue for the other missing service member.
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