Phoom Chairatana on Muck Rack

Phoom Chairatana

As seen in: PLOS ONE, Chemistry World
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Articles

Molecular dynamics simulations of human α-defensin 5 (HD5) crossing gram-negative bacterial membrane

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By Tadsanee Awang, Phoom Chairatana, Prapasiri Pongprayoon, Agricultural Industries
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Awang T, Chairatana P, Pongprayoon P (2023) Molecular dynamics simulations of human α-defensin 5 (HD5) crossing gram-negative bacterial membrane. PLoS ONE 18(11): e0294041. https://doi.org/10.1371/journal.pone.0294041 Editor: Surajit Bhattacharjya, Nanyang Technological University, SINGAPORE Received: July 28, 2023; Accepted: October 24, 2023; Published: November 21, 2023 Copyright: © 2023 Awang et al.
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Imaging plasma membrane phase behaviour in live cells using a thiophene-based molecular rotor

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By Michael Dent, Phoom Chairatana, Ismael Lopez Duarte, Callum J Dickson
| Chemistry World
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Proteolysis triggers self-assembly and unmasks innate immune function of a human α-defensin peptide

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By Phoom Chairatana, Hiutung Chu, Patricia A. Castillo
| Chemistry World
Human α-defensin 6 (HD6) is a unique peptide of the defensin family that provides innate immunity in the intestine by self-assembling to form higher-order oligomers that entrap bacteria and prevent host cell invasion. Here, we report critical steps in the self-assembly pathway of HD6. We demonstrate that HD6 is localized in secretory granules of small intestinal Paneth cells.
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