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Articles by Ping Gu
Primary Tumor Genomics and Patterns of Distant Recurrence in Resected Gastric Cancer
Primary Tumor Genomics and Patterns of Distant Recurrence in Resected Gastric Cancer Key Points Question Can genomic profiling of a primary gastric cancer identify patients at increased risk of recurrence and predict the pattern of metastatic spread after surgical resection? Findings In this cohort study of 438 patients with resected gastric cancer, alterations in KRAS and PIK3CA genes were independently associated with worse disease-free survival.
中美欧人工智能专利政策和法律实践--谁是发明人 - Lexology
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1-hour post-load plasma glucose: a reliable marker of insulin resistance in type 2 diabetes, as determined by the TyG index
Introduction Insulin Resistance (IR): Also referred to as “insulin insensitivity”, is primarily defined by a diminished ability of peripheral tissues to uptake and utilize glucose, particularly skeletal muscle, fat tissue, and the liver, resulting in an impaired response to insulin.
Risk stratification and predictive value of glucose variability for the development of post-acute pancreatitis diabetes mellitus
Introduction Post-acute pancreatitis diabetes mellitus (PPDM-A) is a specifical diabetes subtype that develops following acute pancreatitis (AP) and is characterized by impaired insulin secretion and glucose metabolism (1–3). It is associated with higher rates of morbidity and mortality, as well as a decreased quality of life (4). The reported incidence of PPDM-A varies widely in different studies, ranging from 5% to 70% (5–8).
Diagnostic Value of Serum miR-17-5p in Type 2 Diabetes Mellitus and It
Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 18 Original Research Diabetes Pathophysiology and Complications Authors Gu P, Yu D, Zhang Y, Chai X Received 22 May 2025 Accepted for publication 19 August 2025 Published 4 September 2025 Volume 2025:18 Pages 3237—3247 DOI https://doi.org/10.2147/DMSO.S542183 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Rebecca Conway Ping Gu, Dan Yu, Yu Zhang,...
Association of the Monocyte-to-High Density Lipoprotein Ratio with the
Xueqin Gu,1,* Hongmei Shen,2,* Jiafeng Jiang,1,* Ping Gu,2,* Peilong Liu,2 Zhenguo Zhao,3 Jinfang Ge1 1Department of Dermatology, The Second People’s Hospital of Nantong, Nantong, Jiangsu Province, People’s Republic of China; 2Department of Clinical Laboratory, The Second People’s Hospital of Nantong, Nantong, Jiangsu Province, People’s Republic of China; 3Department of Emergency Medicine, The Second People’s Hospital of Nantong, Nantong, Jiangsu Province, People’s Republic of...
Increased Expression of PDGFA Is Associated With Poor Prognosis and Immune Infiltration in Head and Neck Squamous Cell Carcinoma
Platelet-derived growth factor A (PDGFA) has been shown to be upregulated in several tumors, contributing to their malignant phenotypes. However, its expression and function in head and neck squamous cell carcinoma (HNSC) are not clearly understood. Thus, we aimed to evaluate this issue using bioinformatic analyses and primary experimental validation. The expression of PDGFA was analyzed using popular bio-databases and further validated by RT-PCR and immunohistochemical staining.
Advances in Extracellular-Vesicles-Based Diagnostic and Therapeutic Approaches for Ocular Diseases
1. Introduction Click to copy section linkSection link copied! The human eye is a highly specialized organ containing structures, including the cornea, iris, lens, and retina, which receive a large amount of information from the external world. Therefore, the integrity of each structure is essential for light perception and normal visual function.
Metabolic Regulation of Endothelial Cells: A New Era for Treating Wet Age-Related Macular Degeneration
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Water | Free Full-Text | Response of Floods to the Underlying Surface Changes in the Taojiang River Basin Using the Hydrologic Engineering Center’s Hydrologic Modeling System
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
High-Q and Intense Lattice Plasmon Resonance in Hexagonal Nonclose Packed Thin Silver Nanoshells Array
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Phys. Chem. C 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
浅析人工智能系统训练数据的合规问题
ChatGPT让2023年成了人工智能系统（“AI”）的大年。和ChatGPT一样让人感到震惊的是，AI能找到并理解人类认知范围之外的规律，并据此作出解决方案。 如，AI发现了具有显著效果的抗生素——halicin，但是halicin并未具备人类科学家归纳出来的化学特征。科研人员准备了一个包含了两千多个分子的训练数据集，并按照抗菌效果优劣提前作好标记，让AI在训练过程中可以有的放矢。这是一种经典的机器学习算法——监督学习（supervised learning），即“仅用标注数据进行训练的机器学习”[1]。但是，如果要学习的数据量超出标记能力，AI就需要在大量数据中自动发现其中的规律和联系，这种方式被称为“无监督学习（unsupervised...
Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023)
Graphical Abstract Beige Adipocyte Beige fat is gaining increasing therapeutic interest due to its potential in combating obesity and other non-communicable diseases. By single clone analysis, Tao Nie, Donghai Wu, Hannah Xiaoyan Hui, and co-workers discover that androgen receptor (AR) turns out to be a highly potent transcription factor in suppression of PRDM16, the key molecular switch of beige fat.
Experimental Study on Back-Flushing Characteristics of an In-Vessel Filtration System in Fischer-Tropsch Slurry Reactors
An in-vessel filtration system is a crucial component in commercial low-temperature Fischer–Tropsch slurry reactors for the continuous separation of liquid products and catalysts generated by the reaction. Periodic back-flushing is key to ensuring the stability and continuity of the in-vessel filtration system, but it has been relatively unexplored.
Physical-layer security of optical communication based on chaotic optical encryption without an additional driving signal
Abstract We propose and numerically demonstrate a scheme for physical-layer security based on chaotic phase encryption, where the transmitted carrier signal is used as the common injection for chaos synchronization, so there is no need for additional common driving. To ensure privacy, two identical optical scramblers consisting of a semiconductor laser and a dispersion component are used to observe the carrier signal.
Magnesium hexacyanoferrate nanocatalysts attenuate chemodrug-induced cardiotoxicity through an anti-apoptosis mechanism driven by modulation of ferrous iron | Nature Communications
Abstract Distressing and lethal cardiotoxicity is one of the major severe side effects of using anthracycline drugs such as doxorubicin for cancer chemotherapy. The currently available strategy to counteract these side effects relies on the administration of cardioprotective agents such as Dexrazoxane, which unfortunately has unsatisfactory efficacy and produces secondary myelosuppression.
Two-dimensional hexagonal boron nitride as saturable absorber for a 1.5 µm passively Q-switched erbium-doped fiber laser
Abstract We report on two-dimensional (2D) hexagonal boron nitride (hBN) as saturable absorber (SA) material in a passively $Q$-switched erbium-doped fiber laser (EDFL) operating at 1.5 µm. The 2D hBN film as an SA is fabricated and transferred onto the optical fiber tip by natural deposition technology.
Enforcing patents and trade secrets in China
Over the past decade, patent and trade secret litigation has become increasingly popular in China. This chapter focuses on China’s adjudication system in patent and trade secret cases, on the various ways to collect evidence and the procedures involved. It also looks at recent trends to help foreign companies understand China’s patent and trade secret litigation system and to safeguard their legal rights and interests in China.
In Situ Bone Regeneration Enabled by a Biodegradable Hybrid Double-Network Hydrogel
In Situ Bone Regeneration Enabled by a Biodegradable Hybrid Double-Network Hydrogel Yuanhao Zhang, Mingjiao Chen, Jia Tian, Ping Gu, Hongliang Cao, Xianqun Fan and Weian Zhang Abstract The stem cell therapy based on advanced biomaterials provides a promising strategy in bone tissue engineering. Nevertheless, guiding bone regeneration that fulfills the criteria in terms of biomechanics, biodegradability and bioactivity is highly appealing but challenging.
Coexistence of sensitive and resistant epidermal growth factor receptor (EGFR) mutations in pretreatment non-small cell lung cancer (NSCLC) patients: First or third generation tyrosine kinase inhibitors (TKIs)? - Lung Cancer
Publication HistoryPublished online: January 10, 2018Accepted: January 9, 2018; Received in revised form: December 24, 2017; Received: November 30, 2017;
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