Jiaying Hu
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Single-cell and high-resolution spatial profiling of podocytopathies reveals core mechanisms of podocyte injury
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Podocytes (PODs) play a critical role in maintaining glomerular filtration function, and their injury is a key driver of progressive podocytopathies (PCPs). Despite their clinical importance, the molecular and spatial mechanisms underlying POD injury remain poorly understood.
Spatial distribution characteristics and protection strategies of National intangible cultural heritage in the Pearl river basin
Abstract While the spatial analysis of Intangible Cultural Heritage (ICH) is well-established at national and provincial scales, cross-jurisdictional river basins remain a critical research gap. This study investigates the spatial heterogeneity of 289 national-level ICH items within China’s Pearl River Basin to inform regional conservation planning.
A Comprehensive Analysis of the Impact of Nutrient Intakes on the Stages and Mortality of Cardiovascular-Kidney-Metabolic Syndrome
1 Introduction With the global aging population and shifts in lifestyle, the incidence and mortality of chronic diseases have been steadily rising, particularly those related to cardiovascular, kidney, and metabolic disorders, such as diabetes and obesity (Ren et al. 2024). Due to their strong pathophysiological interconnections, the American Heart Association (AHA) introduced the cardiovascular–kidney–metabolic (CKM) syndrome framework to optimize disease prevention and management (Ndumele et al.
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