Pingying Qing
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Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution
1 Introduction Obstetric antiphospholipid syndrome (OAPS), a subset of antiphospholipid syndrome (APS), is an autoimmune disorder characterized by persistent positive antiphospholipid antibodies (aPLs) in circulation and pathologic pregnancies, including recurrent miscarriage, stillbirth, severe pre-eclampsia, and severe placental insufficiency.[1] Microthrombosis in the maternal-fetal interface was previously regarded as the primary pathogenesis of OAPS, but subsequent studies found that...
Single-cell transcriptome analyses reveal disturbed decidual homoeostasis in obstetric antiphospholipid syndrome
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Single-cell transcriptome analyses reveal disturbed decidual homoeostasis in obstetric antiphospholipid syndrome
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