Pooja Ghosh

Insulin Fibril Inhibition Using Glycopolymeric Nanoassemblies Avisek Bera, Pooja Ghosh, Soumen Barman, Sagnik Bhattacharya, Babu Sudhamalla, Kalyan Goswami and Priyadarsi De Abstract To address the obstacle in insulin protein homeostasis leading to the formation of neurotoxic amyloid plaques associated with different diseases, herein we synthesized block copolymers using the reversible addition-fragmentation chain transfer (RAFT) polymerization method, composed of tert-butoxycarbonyl (Boc)...

Polyisobutylene-based glycopolymers as potent inhibitors for in vitro insulin aggregation Asmita Dey, Ujjal Haldar, Tota Rajasekhar, Pooja Ghosh, Rudolf Faust and Priyadarsi De Abstract A family of amphiphilic diblock copolymers containing hydrophobic polyisobutylene (PIB, Mn = 1000 g/mol) segment and hydrophilic block with sugar pendants has been synthesized by combining living cationic and reversible addition-fragmentation chain transfer (RAFT) polymerization techniques; to explore their...

Fatty Acid-Based Polymeric Micelles to Ameliorate Amyloidogenic Disorders Avisek Bera, Debangana Mukhopadhyay, Kalyan Goswami, Pooja Ghosh, Rumi De and Priyadarsi De Abstract To develop anti-amyloidogenic inhibitors for ameliorating the treatment of diabetes, herein, we have synthesized amphiphilic block copolymers with side-chain fatty acid (FA) moieties via reversible addition fragmentation chain-transfer (RAFT) polymerization.