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Articles

Trans-(±)-TTPG-B Attenuates Cell Cycle Progression and Inhibits Cell Proliferation on Cholangiocarcinoma Cells

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By Potchanapond Graidist, Thidarath Rattanaburee, Tienthong Thongpanchang, Varomyalin Tipmanee
| MDPI
1. Introduction Cholangiocarcinoma (CCA), has been reported to have a hepatocyte origin [1] and is an adenocarcinoma that begins in the bile ducts. Most CCA patients are diagnosed with an advanced and aggressive malignancy that cannot be treated with surgery alone [2]. Targeted therapy is an interesting treatment for improving overall survival and decreasing the undesirable adverse effects of cancer treatment. This treatment uses drugs that bind to a specific protein in cancer [3].
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