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Prabhas Moghe

As seen in: Nature, EurekAlert!
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Articles

Engineering Lineage Potency and Plasticity of Stem Cells using Epigenetic Molecules

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By David Gray, Prabhas Moghe, Anandika Dhaliwal, Sandra Pelka
| Nature Verified
Transplantation of bone tissues is often needed to repair bones damaged due to severe trauma or disease24,25. Conventional autografts, allografts and xenografts have many associated adverse effects (implant rejection, disease transfer) and complications (cost, surgical risks and injury at donor site)26,27. Consequently, there is heightened demand for an alternative bone repair treatment using biocompatible and functional engineered-bone tissue formed from autologous stem cells.
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3-D technology enriches human nerve cells for transplant to brain

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By Prabhas Moghe
| EurekAlert!
National Institutes of Health-funded scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals. The injection of these networks of functioning human neural cells -- compared to injecting individual cells -- dramatically improved their survival following transplantation into mouse brains.
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