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Articles by Qi Hou
Behavioral outcomes after sevoflurane-based general anesthesia in preschool children: a prospective cohort study with perioperative hydrogen sulfide–related biomarker profiling
Abstract The association between general anesthesia (GA) for surgical procedures in preschool children and subsequent neurobehavioral outcomes remains unresolved, and human biomarker data on potential biological correlates are limited.
Research on image fusion noise reduction method based on AFM scanned cell image in tapping
Abstract Scanning cells with tapping-mode atomic force microscopy (TM-AFM) often introduces significant noise in the central region of the topography image, whereas the corresponding amplitude image remains relatively clear. Leveraging the strong correlation between these two image types, this study proposes a noise reduction method for cellular topography images through the fusion of amplitude and topography data.
Rapid and ultrasensitive detection of telomerase activity in clinical samples using a PCR-free enzymatic assay
Abstract Telomerase, a critical biomarker for cancer diagnosis, necessitates the development of convenient, efficient, and highly sensitive detection methods. Distinct from conventional nucleic acid amplification techniques such as PCR, LAMP, or RCA, this method achieves signal amplification through Endo IV-mediated enzymatic turnover.
Association of the CD14 gene rs2569190 polymorphism with the risk of allergic rhinitis: a systematic review and meta-analysis
Abstract Allergic rhinitis (AR) is a type I hypersensitivity disease of the nasal mucosa that is mediated by immunoglobulin E (IgE). The relationship between the rs2569190 polymorphism of the CD14 gene and the risk of AR remains unclear. Therefore, we performed a meta-analysis to evaluate this relationship. We performed a systematic search and found 8 relevant publications that were included in this meta-analysis, consisting of 1,022 cases and 1,045 controls.
Sitosterolemia carrying both ABCG5 and HBA gene mutations: a case report and review of the literature - Journal of Medical Case Reports
Sitosterolemia is a rare disorder characterized by elevated levels of phytosterols, low-density lipoprotein (LDL), and cholesterol. The complications associated with sitosterolemia arise from the deposition of phytosterols in various tissues. Patients exhibit a range of symptoms, with considerable heterogeneity, such as xanthomas in different locations.
An electrochemical sensor based on an amino-functionalized metal-organic framework for the highly sensitive detection of glutamate
An electrochemical sensor based on an amino-functionalized metal–organic framework for the highly sensitive detection of glutamate† Glutamate serves as an essential excitatory neurotransmitter in the central nervous system and participates in numerous biochemical processes in living organisms. In this research, an ultra-high sensitivity electrochemical sensor was engineered for the detection of glutamic acid.
Single-cell sequencing uncovers a high ESM1-expression endothelial cell subpopulation associated with bladder cancer progression and the immunosuppressive microenvironment | Scientific Reports
Abstract Despite remarkable advancements in therapeutic strategies, a considerable proportion of patients with bladder cancer (BC) still experience disease progression and unfavorable prognosis. The heterogeneity and biological functions of tumor endothelial cells (ECs) during BC progression remain poorly understood. We collected scRNA-seq data from BC samples and identified two EC subpopulations through hierarchical clustering analysis.
Exposure to arsenic and cognitive impairment in children: A systematic review
Loading metrics Open Access Peer-reviewed Research Article Citation: Tian Y, Hou Q, Zhang M, Gao E, Wu Y (2025) Exposure to arsenic and cognitive impairment in children: A systematic review. PLoS ONE 20(2): e0319104.
Inundation Characteristics’ Prediction of Storm Surge under Relative Sea Level Rise Scenarios: A Case Study of Taizhou, Zhejiang Province
1. Introduction Relative sea level rise (RSLR) is the result of the combined effect of absolute sea level rise, land subsidence and tectonic crustal moving [1], which make RSLR irreversible. On the one hand, due to the inherent hysteresis of the climate system, absolute sea level rise caused by global climate change will continue for a long time after greenhouse gas concentrations stabilize, which is inevitable [2].
Pharmaceutics | Free Full-Text | Liquid Chromatography-Mass Spectrometry Analytical Methods for the Quantitation of p-Cresol Sulfate and Indoxyl Sulfate in Human Matrices: Biological Applications and Diagnostic Potentials
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Regioselective 5-exo-dig (halo)cyclization of N-propargyloxycarbonyl guanidine derivatives under mild condition
Regioselective 5-exo-dig (halo)cyclization of N-propargyloxycarbonyl guanidine derivatives under mild condition A highly regioselective 5-exo-dig cyclization of aromatic N-propargyloxycarbonyl guanidines was developed via Ag(I)-catalyzed intramolecular hydroamination reaction. This method features fast reaction rate and mild reaction condition.
Insight into the Critical Role of Oxygen Vacancies and V=O Bonds Length in V2O5 for Advanced Zinc Ion Storage
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Applicability Evaluation of the Global Synthetic Tropical Cyclone Hazard Dataset in Coastal China
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Research status, opportunities, challenges of cobalt phosphate based materials as OER electrocatalysts
Research status, opportunities, challenges of cobalt phosphate based materials as OER electrocatalysts Although water splitting is currently the most promising technology for preparing green hydrogen on a large scale, the high energy consumption has limited its industrial application. The sluggishness of the oxygen evolution reaction (OER) at the anode hinders the electrolysis efficiency of water splitting.
ReACT (Redox-Activated Chemical Tagging) chemistry enables direct derivatization and fluorescent detection of S-adenosyl-L-homocysteine (SAH)
ReACT (Redox-Activated Chemical Tagging) chemistry enables direct derivatization and fluorescent detection of S-adenosyl-L-homocysteine (SAH) S-Adenosyl-L-homocysteine (SAH) is a universal byproduct and product inhibitor of methyltransferase-catalyzed methylation reaction. Here based on ReACT (Redox-Activated Chemical Tagging) chemistry, direct derivatization and fluorescent measurement of SAH were achieved with features such as mild reaction condition and simple operation.
Sevoflurane upregulates neuron death process-related Ddit4 expression by NMDAR in the hippocampus
Abstract Postoperative cognitive dysfunction (POCD) is a serious and common complication induced by anesthesia and surgery. Neuronal apoptosis induced by general anesthetic neurotoxicity is a high-risk factor. However, a comprehensive analysis of general anesthesia-regulated gene expression patterns and further research on molecular mechanisms are lacking.
Sevoflurane upregulates neuron death process-related Ddit4 expression by NMDAR in the hippocampus
Research Paper Volume 15, Issue 12 pp 5698—5712 1 Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China https://doi.org/10.18632/aging.204822 How to Cite Copyright: © 2023 Li et al.
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