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Qinqin Liang

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Articles

Structural and mechanistic insights into OCTN1-mediated transport and cancer cell proliferation

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By Binghong Xu, Shengjian Liang, Ziyu Wang, Xiaoyu Zhou, Liuying Wang, Xiaoke Liu, Wei Guo, Cheng Zhu, Zhiyong Lou, Yaxin Wang, Qinqin Liang
| Nature Verified
Abstract The Novel Organic Cation Transporter 1 (OCTN1) facilitates the uptake of endogenous metabolites and therapeutic drugs across diverse tissues. Recognized as a key transporter for the antioxidant ergothioneine (ET), OCTN1 also mediates the cellular entry and release of various cationic compounds. Dysregulation of OCTN1 has been implicated in cancer progression and drug interaction.
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