Qiuying Chen
As seen in:
Wiley Online Library,
Frontiers,
MDPI,
ACS Publications,
Medscape,
BioRxiv,
EClinicalMedicine,
Cell Press,
eLife,
Texas Medical Center
and
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Spatial deconstruction of the plasma membrane
Abstract The plasma membrane of cells is known to be heterogeneous with regards to the spatial distribution of proteins and lipids, but the nature and origins of this heterogeneity are unclear. In this study we perform fluorescence microscopy on plasma membrane sheets and find that most proteins occur in protein-rich domains separated by intervening protein-poor regions.
Transcription Factor ATF4 Deletion Reprograms Glucose Metabolism in Clear Cell Renal Cell Carcinoma.
Background/Objectives: Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer. Human ccRCCs have increased glycolytic metabolism and decreased mitochondrial oxidative metabolism relative to normal kidneys.
The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming
eLife Assessment This study provides new and interesting findings that SCoR2 acts as a denitrosylase to control cardioprotective metabolic reprogramming and prevent injury following ischemia/reperfusion. The compelling evidence is supported by a novel multi-omics approach, but questions remain regarding the stability and human relevance of BDH1 as well as the sufficiency of SCoR2.
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