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Reduced laser-evoked potential habituation detects abnormal central pain processing in painful radiculopathy patients
Repetitive painful laser stimuli lead to physiological laser-evoked potential (LEP) habituation, measurable by a decrement of the N2/P2 amplitude. The time course of LEP-habituation is reduced in the capsaicin model for peripheral and central sensitization and in patients with migraine and fibromyalgia. In the present investigation, we aimed to assess the time course of LEP-habituation in a neuropathic pain syndrome, i.e. painful radiculopathy.
Prediction of response to tapentadol in chronic low back pain
MR has received travel reimbursement from Grünenthal. PH has received speaking fees from Pfizer and Genzyme and travel reimbursement from Grünenthal. JG has received speaker fees and travel support from Pfizer and Grünenthal and consultancy fees from Glenmark. AB received honoraria from Astellas, Pfizer, Allergan, Grünenthal, Boehringer Ingelheim, Bayer and advisory from Grünenthal, Genzyme, Pfizer, Boehringer Ingelheim and Bayer. AB received Grants/research support by Pfizer.
Cold-evoked potentials - Ready for clinical use?
PH has received speaking fees from Pfizer Pharma GmbH, Germany and Genzyme GmbH, Germany and travel reimbursement from Grünenthal. AN none declared. AB received honoraria from Astellas Pharma GmbH, Germany, Pfizer Pharma GmbH, Germany, Allergan Inc. US, Grünenthal, Boehringer Ingelheim, Bayer and advisory from Grünenthal, Genzyme GmbH, Germany, Pfizer Pharma GmbH, Germany, Boehringer Ingelheim Pharma GmbH & Co.KG, Germany and Bayer. AB received Grants/research support by Pfizer.
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