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Rachel Barocio on Muck Rack

Rachel Barocio

As seen in: Cell Press
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Articles

Synthetic Cassettes for pH-Mediated Sensing, Counting, and Containment

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By Finn Stirling, Alexander D. Naydich, Juliet Bramante, Rachel Barocio
| Cell Press Verified
Highlights • Containment system with an escape frequency below the detection limit of 10−11 • Evolutionary stability achieved through toxin-antitoxin balancing • Pulse counter developed that responds to the falling edge of a signal • Counter will not advance unless 2 distinct signals are registered Summary As pH is fundamental to all biological processes, pH-responsive bacterial genetic circuits enable precise sensing in any environment.
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