Radhakrishnan Sabarinathan

Correction to: Nature Genetics https://doi.org/10.1038/s41588-025-02153-x, published online 8 April 2025. In the version of this article initially published, the name of Kumarasamy Thangaraj appeared incorrectly (as Thangaraj Kumarasamy), while names of authors in the GenomeIndia Consortium were listed incorrectly: L. S. Shashidhara (as L. S. Shashishara), Lal Nundanga (as Lalnundanga), Saurav Roy (as Sourav Roy), Pratheusa Machha (as Pratheusa Maccha), and Ankit Mukherjee (as Ankit Mukerji).

The rich ethnolinguistic and sociocultural differences that exist in India offers a unique opportunity to study human diversity. With the whole genomes of 10,000 healthy and unrelated Indians from 83 populations, the GenomeIndia project captures the genetic diversity of one of the highly underrepresented populations in the global genomics landscape.

Immune checkpoint proteins are expressed on tumour or immune cells and their inhibition using immune checkpoint inhibitors (ICIs) can enhance anti-tumour immunity. However, currently used biomarkers do not always reliably predict response, highlighting the need to find additional biomarkers. Work by Kalaora et al. demonstrates that expression of the immunoproteasome, a specialized form of the proteasome, could be a potential biomarker for ICI response in melanoma.