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Reid Larsen

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Articles

Multi-omic analysis reveals the unique glycan landscape of the blood-brain barrier glycocalyx

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By Reid Larsen, Krzysztof Kucharz, Sidar Aydin, Biswa P. Choudhury
| biorxiv.org
Abstract The blood-brain barrier (BBB) glycocalyx is the dense layer of glycans and glycoconjugates that coats the luminal surface of the central nervous system (CNS) vasculature. Despite being the first point of contact between the blood and brain, not much is known about the BBB glycocalyx. Here, we performed a multi-omic investigation of the BBB glycocalyx which revealed a unique glycan landscape characterized by enrichment of sialic acid, chondroitin sulfate, and hyaluronan.
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By Granton A. Jindal, Joe J Solvason, Sophia Le, Benjamin P. Song, Adam Klie, Michelle F. Ragsac, Kelly A. Frazer, Reid Larsen, Emma K. Farley, Alexis T. Bantle, Jessica L. Grudzien, Agnieszka D’Antonio-Chronowska, Fabian Lim
| Cell Press Verified
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Unraveling the coordinated dynamics of protein- and metabolite-mediated cell-cell communication

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By Erick Armingol, Reid Larsen, Hratch M. Baghdassarian, Martin Cequeira
| biorxiv.org
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