Renad Jabarin

Keywords emotion recognition social behavior prelimbic cortex pyramidal neurons fiber photometry single-unit recordings optogenetic manipulations Get full text access Log in, subscribe or purchase for full access. References 1. Adolphs, R. Social cognition and the human brain Trends Cogn. Sci. 1999; 3:469-479 2. Frith, C.D. ∙ Frith, U. Mechanisms of social cognition Annu. Rev. Psychol. 2012; 63:287-313 3. Adolphs, R.

Abstract The ability to perceive the emotional states of others, termed emotion recognition, allows individuals to adapt their conduct to the social environment. The brain mechanisms underlying this capacity, known to be impaired in individuals with autism spectrum disorder (ASD), remain, however, elusive. Using the emotional state preference paradigm, we show that adult mice can discern emotional states of conspecifics in a sex-specific manner, behavior impaired in an ASD mouse model.

Abstract Individuals diagnosed with autism spectrum disorder (ASD) show difficulty in recognizing emotions in others, a process termed emotion recognition. While human fMRI studies linked multiple brain areas to emotion recognition, the specific mechanisms underlying impaired emotion recognition in ASD are not clear, partially due to the lack of appropriate tests in animal models.