Rhiannon Bree Werder

As seen in: The Journal of Allergy & Clinical Immunology

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Eosinophils apply a handbrake to plasmacytoid dendritic cell antiviral immunity in asthma

Jul 30, 2022 |

By Simon Phipps, Daniel Howard, Rhiannon Bree Werder

| The Journal of Allergy & Clinical Immunology

Virus-induced IFN-α secretion by plasmacytoid dendritic cells (pDCs) is negatively impacted by IgE and has been linked to asthma exacerbations. Eosinophils, another contributor to type 2 inflammation, are also associated with asthma severity.

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Eosinophils apply a handbrake to plasmacytoid dendritic cell antiviral immunity in asthma

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