Rhys Brady

Introduction Mild traumatic brain injury (mTBI) has an estimated annual incidence of 64–74 million worldwide.1 mTBI often results in debilitating short-term symptoms, and there is evidence that >50% of mTBI patients experience persisting symptoms for months to years after the injury.2–4 mTBI is also a risk factor for the later development of neurodegenerative conditions such as dementia,5 Parkinson’s disease,6 and chronic traumatic encephalopathy.7 Despite the high incidence of mTBI and risk...

Introduction Traumatic brain injury (TBI) is induced by mechanical forces applied to the brain and is a common consequence of vehicular accidents, slips/falls, assaults, as well as work-, sport-, and military-related injuries.1 It is a leading cause of death and disability worldwide, and there is currently no effective treatment known to mitigate the neurodegenerative aftermath that occurs in TBI survivors.1 Studies have identified the misfolding of several proteins in the outcomes of TBI.2–9...