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Richard Phillips

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Articles

Point-of-care multiplexed detection of cytokines using a HexaPie electrode array for asthma endotyping - npj Biosensing

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By Fatima Rizvi, Sasya Madhurantakam, Nana Kwame Ayisi-Boateng, Ernest Adankwah, Michael Ansah, Richard Phillips, Shalini Prasad, Aleeza Qureshi, Salsabil Aziz
| Nature Verified
Abstract Accurate multiplexed cytokine quantification in complex biofluids is essential for immune monitoring and respiratory disease phenotyping. We report HexaPie, a label-free, non-faradaic impedance biosensor that enables simultaneous detection of IL-8, IL-10, and IP-10 in human saliva through electrical double-layer (EDL) modulation at spatially multiplexed gold microelectrodes.
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Changes in phenology mediate vertebrate population responses to temperature globally - Nature Communications

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By Viktoriia Radchuk, Nina McLean, Anne Charmantier, Ray T. Alisauskas, Sergio Ancona, Peter Arcese, Debora Arlt, Karl Berg, Dominique Berteaux, Daniel T. Blumstein, Ulrich Brose, Lyanne Brouwer, Paulo Catry, Andre Chiaradia, Alexandre Courtiol, Francis Daunt, F. Stephen Dobson, Tapio Eeva, Dominique Fauteux, Gilles H Gauthier, Meritxell Genovart, Jonas Hentati-Sundberg, Jose Manuel Igual, Fredric J. Janzen, Stephanie Kramer-Schadt, Sue A. Lewis, Mark L. Mallory, Julien Martin, Manuel Massot, Erik Matthysen, Jean-Baptiste Mihoub, Anders Pape Møller, Mark Newell, Steffen Oppel, Daniel Oro, Santiago Ortega, Tomas Pärt, Josephine M. Pemberton, Richard Phillips, Neville Pillay, Jesús M. Avilés, Heiko G. Rödel, Ana Sanz-Aguilar, Holger Schielzeth, Ben Sheldon, Giacomo Tavecchia, Corey E. Tarwater, Vincent A. Viblanc, Stephanie Jenouvrier, Steven R. Beissinger, Marcel E. Visser, Thomas Reed, Lise M. Aubry, Vebjørn Veiberg
| Nature Verified
Abstract Phenotypic responses to climate affect individual fitness, but the extent to which this translates into effects on population dynamics remains poorly understood. We assemble 213 time series on phenotypes and population sizes of wild vertebrates globally and match them with local climate data. Our meta-analysis shows that morphological traits are mostly climate insensitive.
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Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology - British Journal of Cancer

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By Richard Phillips, Bristi Basu, Natalie Cook, Simon J Crabb, Alastair Greystoke, Juanita Lopez, Magdalena Meissner, Brent O’Carrigan, Eileen Parkes, Patricia Roxburgh, Debashis Sarker, Kienan Savage, Stefan N. Symeonides, Aditi Vedi, Harriet Walter, Gary Middleton
| Nature Verified
Abstract The Experimental Cancer Medicine Centre (ECMC) Network supports UK-wide access to experimental cancer therapies, many of which require specific genomic alterations. This study aimed to develop expert consensus on essential genes for a pan-cancer sequencing panel, involving subject matter experts (SMEs) from the ECMC Network and the pharmaceutical industry. A pilot with 8 SMEs graded 526 genes, refining the list to 210.
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