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Rienke Uijen

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Articles

Tracking spatio-temporal dynamics of early immune responses to an intranasal OMV-based pneumococcal vaccine candidate in mice

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By Rona Roverts, Bram van Cranenbroek, Fred van Opzeeland, Ben Joosten, Esther van Rijssen, Joen Luirink, Dimitri A. Diavatopoulos, Marien de Jonge, Sajida Kanwal, Shaina Vivienne To, Rienke Uijen, Bart van den Berg van Saparoea, Christa E. van der Gaast-de Jongh, Lucille F. van Beek
| Nature Verified
Abstract Outer membrane vesicle (OMV)-based vaccines elicit strong immune responses and have emerged as a versatile platform for targeting multiple pathogens, yet the mechanisms underlying their efficacy remain incompletely understood. Here, we investigated the early immune response following intranasal administration of an OMV-based pneumococcal vaccine candidate in mice.
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