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Rizvangul Iminova on Muck Rack

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From PEGylation to Next-Generation Polymers: Overcoming Biological Barriers - A Review

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By Gulzat Berganayeva, Daniil Shepilov, Rizvangul Iminova, Almagul Almabekova
| Preprints.org
Submitted: 19 January 2026 You are already at the latest version Poly(ethylene glycol) (PEG) has long stood as the prevailing standard in drug delivery, celebrated for its capacity to enhance solubility, extend circulation, and improve pharmacological performance. Nevertheless, the emergence of anti-PEG antibodies, accelerated clearance, and limited biodegradability increasingly undermine its role as a universal solution.
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