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Robert Hatch

As seen in: Fisheries Magazine, Wiley Online Library, PNAS, Medscape, Deseret News, The Nation, JNeurosci, Scraps From the Loft
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Articles

The Effect of Advancing Age and Intraocular Pressure Injury on Retinal Ganglion Cell Function and Synaptic Connectivity

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By Vicki Chrysostomou, Sevannah A Ellis, Lewis E. Fry, Robert Hatch
| Wiley Online Library Verified
AIS axon initial segment AP action potential eEPSC evoked excitatory postsynaptic current eIPSC evoked inhibitory postsynaptic current ERG electroretinogram IOP intraocular pressure pSTR positive scotopic threshold response RGC retinal ganglion cell VEP visual evoked potential 1 Introduction Vision loss from glaucoma results from the selective dysfunction and eventual death of retinal ganglion cells (RGCs) and constitutes a leading cause of global blindness.
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Laboratory and field evaluation of a new light‐emitting‐diode‐lit quatrefoil light trap for sampling fish early life stages

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By Catherine Adams, Robert Hatch, M. Tildon Jones, Randlett Unit
| Fisheries Magazine Verified
MANAGEMENT BRIEF This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1002/nafm.10931.
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Carbogen-Induced Respiratory Acidosis Blocks Experimental Seizures by a Direct and Specific Inhibition of NaV1.2 Channels in the Axon Initial Segment of Pyramidal Neurons

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By Robert Hatch, Ben Rollo, Frank Rigo, Kai Kaila
| JNeurosci Verified
Abstract Brain pH is a critical factor for determining neuronal activity, with alkalosis increasing and acidosis reducing excitability. Acid shifts in brain pH through the breathing of carbogen (5% CO2/95% O2) reduces seizure susceptibility in animal models and patients. The molecular mechanisms underlying this seizure protection remain to be fully elucidated. Here, we demonstrate that male and female mice exposed to carbogen are fully protected from thermogenic-triggered seizures.
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