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Robin Bartolini on Muck Rack

Robin Bartolini

As seen in: Nature, Cell Press, medRxiv, JACC (Journal of the American College of Cardiology)
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Articles

ACKR2 aids the regulation of bone marrow eosinophils to promote monocyte differentiation and anti-bacterial immunity

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By Gillian Wilson, Lily Koumbas Foley, Zuzanna Pocalun, Elise Pitmon, Ayumi Fukuoka, Kit Lee, Lauren Fernandez, Heather Mathie, Robin Bartolini, Laura Medina-Ruiz, John Cole, Gerard Graham
| Nature Verified
Abstract Chemokine receptors control cell migration within the body. Here we reveal interactions between eosinophils and monocytes in the bone marrow, indirectly controlled by the atypical chemokine receptor ACKR2. In the absence of ACKR2, there are decreased numbers of eosinophils in the bone marrow. As a result, eosinophil and monocyte interactions are reduced within the bone marrow niche, and are associated with changes in monocyte gene expression.
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Immune Profiling Identifies Inflammatory Signatures in Immune Checkpoint Inhibitor–Related Myocarditis

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By Douglas Daoudlarian, Sarah Boughdad, Robin Bartolini
| JACC (Journal of the American College of Cardiology)
Methods The study was approved by the Cantonal Ethics Committee of Vaud (CER-VD) under the Immuno-TOX protocol (CER-VD 2022-01030) and conducted in accordance with the Swiss Federal Act on Research involving Human Beings. Biological samples were collected during routine clinical care.
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Distinct immune signatures are a potent tool in the clinical management of cytokine-related syndrome during immune checkpoint therapy

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By Douglas Daoudlarian, Amandine Ségot, Sofiya Latifyan, Robin Bartolini
| medRxiv
MO received honoraria and speaker fees from Moderna, Roche and BMS. The study was funded by CHUV institutional funding I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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