Rongjun Chen on Muck Rack

Rongjun Chen

  • Editor, Chemical Engineering Journal, Elsevier
London
As seen in: Elsevier, Nature, Wiley Online Library, PLOS, MDPI, PNAS, Royal Society of Chemistry, Chemistry World
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Articles

A skin-permeable polymer for non-invasive transdermal insulin delivery - Nature

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By Zhuxian Zhou, Yu Geng, Yue Yuan, Quan Zhou, Mingyu Xu, Shiqun Shao, Jiajia Xiang, Rongjun Chen, Ruhong Zhou
| Nature Verified
Abstract Non-invasive skin permeation is widely used for convenient transdermal delivery of small-molecule therapeutics (less than 500 Da) with appropriate hydrophobicities1. However, it has long been deemed infeasible for large molecules—particularly polymers, proteins and peptides2,3—due to the formidable barrier posed by the skin structure.
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Reliability Evaluation of MMC‐MTDC System Considering Device Failure Rates and Multi‐State Transition

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By Xiaoming Zha, Meng Huang, Rongjun Chen, Zhimin Lu
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. References 1, , , and , “VSC-HVDC Interties for Urban Power Grid Enhancement,” IEEE Transactions on Power Systems 36, no. 5 (2021): 4745–4753. 2, “Updated Review of the Life and Reliability Models for HVDC Cables,” IEEE Transactions on Dielectrics and Electrical Insulation 30, no. 4 (2023): 1371–1390.
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A Bioinspired Pseudopeptide-based Intracellular Delivery Platform Enhances the Cytotoxicity of a Ribosome-inactivating Protein through Multiple Death Pathways

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By Gabriella Morrison, Nicole Henry, Rongjun Chen, Michal Kopytynski
| Royal Society of Chemistry Verified
A Bioinspired Pseudopeptide-based Intracellular Delivery Platform Enhances the Cytotoxicity of a Ribosome-inactivating Protein through Multiple Death Pathways Saporin is a 28,621 Da protein and plant toxin possessing rRNA N-glycosidase activity. Due to its potent ribosome-inactivating ability, saporin is commonly studied as an anticancer agent. However, its enzymatic activity is greatly hindered by its poor plasma membrane permeability.
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