Ronni Eg Sahl

1 INTRODUCTION Accumulation of abdominal fat is suggested to impose a greater risk for cardiometabolic disease, than obesity per se.1 Specifically, accumulation of liver fat (LF) content and visceral adipose tissue (VAT) is associated with liver insulin resistance, accelerated gluconeogenic flux, and increased endogenous glucose production,2 which have been suggested to be a key driver of the development of dyslipidemia, hyperglycemia, and over time cardiometabolic disease.3 It is well...

Abstract and Introduction Abstract Introduction: Statins are widely used in both primary and secondary prevention of cardiovascular disease. The treatment increases the risk of muscle pain (myalgia) which can affect muscle function and levels of physical activity. We investigated whether statin-associated myalgia is coupled to impaired aerobic exercise performance including fat oxidation as well as impaired muscle strength.