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Rosanna Huchzermeier on Muck Rack

Rosanna Huchzermeier

As seen in: Nature, MDPI, BioRxiv, eLife
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Articles

Deficiency of the aryl hydrocarbon receptor in kidney epithelial cells does not influence the development of atherosclerosis

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By Rosanna Huchzermeier, Manuel Rogg, Christoph Schell, Caron Romel, Kathrin Abschlag, Emiel P. C. van der Vorst
| Nature Verified
Abstract The aryl hydrocarbon receptor (AHR) is recognised as an important mediator of inflammatory processes, including those in kidney health. Patients suffering from kidney diseases have an increased risk of cardiovascular diseases, such as atherosclerosis.
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Establishment of a 3D Multicellular HCC Tumor Spheroid Model to Unravel Nrf2’s Influence on the Tumor Immune Microenvironment

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By Nicole Böttcher, Rosanna Huchzermeier, Philipp Krumm, Lara Berschkeit
| Preprints.org
Submitted: 26 January 2026 You are already at the latest version Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death, yet adequate in vitro models mimicking the tumor immune microenvironment (TIME) are rare. Specifically, the role of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) in modulating interactions between tumor cells and tumor-associated macrophages (TAMs) is not fully understood.
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MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

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By Leonida Rakateli, Rosanna Huchzermeier, Andrea Bonnin-Marquez, Sanne L. Maas
| eLife
eLife Assessment This study presents valuable insights into the involvement of miR-26b in the progression of metabolic dysfunction-associated steatohepatitis (MASH). The delivery of microRNA-containing nanoparticles to reduce MASH severity has practical implications as a therapeutic strategy.
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