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Roza Berhanu Lemma on Muck Rack

Roza Berhanu Lemma

As seen in: The Journal of Biological Chemistry
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Articles

The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression

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By Fernando A. Rodriguez-Castañeda, Roza Berhanu Lemma, Ignacio Cuervo, Mads Bengtsen
| The Journal of Biological Chemistry Verified
The small ubiquitin-like modifier (SUMO) post-translationally modifies lysine residues of transcription factors and co-regulators and thereby contributes to an important layer of control of the activities of these transcriptional regulators. Likewise, deSUMOylation of these factors by the sentrin-specific proteases (SENPs) also plays a role in gene regulation, but whether SENPs functionally interact with other regulatory factors that control gene expression is unclear.
Open in Who Shared Issue with article?

The SUMO protease SENP1 and the chromatin remodeller CHD3 interact and jointly affect chromatin accessibility and gene expression

|
By Fernando A. Rodriguez-Castañeda, Roza Berhanu Lemma, Ignacio Cuervo, Mads Bengtsen
| The Journal of Biological Chemistry Verified
The small ubiquitin-like modifier (SUMO) post-translationally modifies lysine residues of transcription factors and co-regulators and thereby contributes to an important layer of control of the activities of these transcriptional regulators. Likewise, deSUMOylation of these factors by the sentrin-specific proteases (SENPs) also plays a role in gene regulation, but whether SENPs functionally interact with other regulatory factors that control gene expression is unclear.
Open in Who Shared Issue with article?
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