Skip To Main Content
Rucha Arun Bapat on Muck Rack

Rucha Arun Bapat

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Rucha Arun

Contact Rucha Arun, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Ameloblastin amphipathic helix motif mediates ameloblast polarization and prismatic enamel formation

|
By Jing Cai, Derk Joester, Natalie C. Kegulian, Edwin Sarkisians, Marziyeh Aghazadeh, Simon Webster, Janet Moradian-Oldak, Gayathri Visakan, Rucha Arun Bapat, Ethan Trevor Suwandi
| Nature Verified
Abstract Ameloblastin (Ambn) is a tooth-specific multifunctional protein essential for enamel biomineralization and the formation of its prismatic microstructure. To examine the function of the evolutionarily conserved cell-binding Ambn amphipathic helix (AH) motif, we deleted the hydrophobic residues within the Ambn AH motif in genetically engineered mice. Enamel in the homozygous (AmbnΔL76-P86) mutants had normal thickness but was hypo-mineralized and lacked prismatic structure.
Open in Who Shared Issue with article?
See all 1 articles