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Rulian Zhao on Muck Rack

Rulian Zhao

As seen in: Nature, Mary Ann Liebert, Inc.
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Articles

KIF11 prevents retinal endothelial ferroptosis in familial exudative vitreoretinopathy by inhibiting phosphorylation-driven PRDX1 phase separation

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By Rulian Zhao, Li Peng, Liting Lv, Yunqi He, Huijuan Xu, Xiang Zhang, Peiquan Zhao, Shujin Li, Zhenglin Yang, Lanyao Yang, Xu Ha
| Nature Verified
Abstract Familial exudative vitreoretinopathy is a hereditary disorder predominantly affecting infants and young children, often leading to severe vision loss. Approximately 40% of patients carry mutations in Norrin/β-catenin pathway genes. Nevertheless, the downstream pathogenic mechanisms remain unclear. Here, by using bulk RNA sequencing and single-cell RNA sequencing analyses, we identify KIF11 as a key downstream effector in retinal endothelial cells.
Open in Who Shared Issue with article?

Whole-Exome Sequencing Reveals Novel TSPAN12 Variants in Autosomal Dominant Familial Exudative Vitreoretinopathy

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By Chen Chen, Lulin Huang, Rulian Zhao, Periasamy Sundaresan
| Mary Ann Liebert, Inc.
Introduction Familial exudative vitreoretinopathy (FEVR), a hereditary disorder that affects the peripheral vascularization of the retina, was first described by Criswick and Schepens (Criswick and Schepens, 1969).
Open in Who Shared Issue with article?
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