Runzhu Yuan

Keywords DKD TFRC Lactylation Ferroptosis p300 Introduction Diabetes is a chronic metabolic disorder that affects most major organs of the body[1]. In 2019, about 463 million people globally had diabetes. According to relevant statistical projections, the number of people with diabetes is expected to rise to 700 million by 2045[2]. Proximately 30% to 40% of individuals with diabetes will develop diabetic kidney disease (DKD) during their lifetime[3-4].

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