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Sex and regional differences in gene expression across the striatum in psychosis - Translational Psychiatry
Abstract Psychosis is a hallmark symptom of schizophrenia and highly prevalent in bipolar disorder. Previous work has shown altered gene expression within subregions of the striatum in subjects with psychosis, but it is unclear if these alterations differ across subregions.
Response to the Commentary on “Experimental Design and Power Calculation in Omics Circadian Rhythmicity Detection Using the Cosinor Model”
We agree and highly appreciate the correction of the non-central parameter (ncp) in the power calculation by Dr. Westermark. We acknowledge the mathematical mistake in our derivation.
Development and evaluation of a machine learning model to predict acute care for opioid use disorder among Medicaid enrollees engaged in a community‐based treatment program
INTRODUCTION Opioid use disorder (OUD) is a significant public health concern in the United States (US) including Pennsylvania (PA). In 2021, Pennsylvania had the ninth highest drug overdose death rate (43.2 per 100 000) in the United States. [1] In response to the rising rates of OUD, the PA Department of Human Services introduced the PA OUD Centers of Excellence (COE) program in 2016 as an innovative community-based delivery model for addressing OUD among Medicaid enrollees [2].
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