Rutsuko Ito on Muck Rack

Rutsuko Ito

Scarborough
As seen in: Nature, Frontiers, eLife
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Articles

Sex-dependent role of the ventral hippocampus, but not its projection to the medial prefrontal cortex, in a novel operant conflict-driven ethanol choice task

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By Tanner McNamara, Yuxi Chen, Michelle Wang, Andy Lee, Rutsuko Ito, Jonathan Manoon
| Nature Verified
Abstract Sex differences in approach-avoidance decision making with sucrose rewards are well documented, with males exhibiting greater conflict approach behavior and females exhibiting greater conflict avoidance. Consistent with this, previous work has shown that approach bias under conflict in males reliably predicts persistent operant ethanol self-administration under punishment.
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Male rodent perirhinal cortex, but not ventral hippocampus, inhibition induces approach bias under object-based approach-avoidance conflict

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By Sandeep Dhawan, Andy Lee, Rutsuko Ito, Carl Pinter
| eLife
Abstract Neural models of approach-avoidance (AA) conflict behavior and its dysfunction have focused traditionally on the hippocampus, with the assumption that this medial temporal lobe (MTL) structure plays a ubiquitous role in arbitrating AA conflict.
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Parallel ventral hippocampus-lateral septum pathways differentially regulate approach-avoidance conflict - Nature Communications

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By Rutsuko Ito, Sajeevan Sujanthan
| Nature Verified
Abstract The ability to resolve an approach-avoidance conflict is critical to adaptive behavior. The ventral CA3 (vCA3) and CA1 (vCA1) subfields of the ventral hippocampus (vHPC) have been shown to facilitate avoidance and approach behavior, respectively, in the face of motivational conflict, but the neural circuits by which this subfield-specific regulation is implemented is unknown.
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