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Sabihur Rahman on Muck Rack

Sabihur Rahman

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A comparative study of hepatitis B virus X protein mutants K130M, V131I and KV130/131MI to investigate their roles in fibrosis, cirrhosis and hepatocellular carcinoma - Siddiqui - 2017 - Journal of Viral Hepatitis - Wiley Online Library

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By Syed F. Ali, Zaheenul Islam, Sabihur Rahman, Syed Naqui
| Color Research & Application Verified
Hepatitis B virus (HBV) genomic mutations A1762T, G1764A and AG1762/1764TA cause production of HBV X protein (HBx) mutants, namely K130M, V131I and KV130/131MI. These mutations are important biomarkers for the development of cirrhosis and hepatocellular carcinoma (HCC) in chronic HBV patients. The present study comparatively analyzes the impact of intracellular expression of HBx mutants on HCC cell line Huh7.
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