Sakura Muramoto

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Submitted: 07 January 2025 You are already at the latest version Infection with Porphyromonas gingivalis (Pg), which is a major periodontal pathogen, causes a large number of systemic diseases based on chronic inflammation such as diabetes, rheumatoid arthritis and Alzheimer’s disease. However, it remains unclear how Pg can augment local systemic immune and inflammatory responses, because Pg and its virulence factor lipopolysaccharide (LPS) have low biological activities.