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Samantha N. Piekos on Muck Rack

Samantha N. Piekos

Palo Alto
As seen in: Nature, BioRxiv, The Lancet, medRxiv
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Articles

Placental network differences among obstetric syndromes identified with an integrated multiomics approach - Communications Biology

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By Samantha N. Piekos, W. Tony Parks, Jennifer Hadlock, Nathan Price
| Nature Verified
Abstract The placenta is essential for pregnancy, and its dysfunction can harm both mother and fetus. To better understand placental physiology and its disruption in disease, we employ a multiomics approach (transcriptomics, metabolomics, and proteomics) combined with clinical data and histopathology from 321 placentas across conditions: severe fetal growth restriction (FGR), FGR with hypertension (FGR + HDP), severe preeclampsia (PE), and spontaneous preterm delivery (PTD).
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Placental Network Differences Among Obstetric Syndromes Identified With An Integrated Multiomics Approach

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By Samantha N. Piekos, Oren Barak, Andrew Baumgartner, Tianjiao Chu
| BioRxiv
Abstract The placenta is essential for a healthy pregnancy, and placental pathology can endanger both maternal and fetal health. Placental function is affected by dynamic, complex, and interconnected molecular, cellular, and environmental events; therefore, we need a systems biology approach to study disease in normal physiological placenta function.
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Detection of Drug Effect Signals Associated with Adverse Pregnancy Outcomes Using Propensity Score Matching at Scale

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By Yeon Mi Hwang, Samantha N. Piekos, Qi Wei, Nathan Price
| medRxiv
YH and SNP declare no conflict of interest. JJH has received research funding (paid to the institute) from Pfizer, Novartis, Janssen, Gilead and Bristol Myers Squibb. QW has been funded in part by Pfizer, Novartis, and Janssen (paid to the institute). LH and NDP are scientific advisors for Sera Prognostics, a pregnancy diagnostics company and NDP holds stock options. Sera Prognostics is not associated with this study or any of the findings.
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