Samantha Sanchez

Abstract Fluorescent biosensors have advanced biomedical research by enabling direct live-cell measurements of signaling activities. However, current technology offers limited resolution and dimensionality, impeding our ability to resolve and interrogate spatiotemporally regulated networks of signaling activities.

Abstract Fluorescent biosensors revolutionized biomedical science by enabling the direct measurement of signaling activities in living cells, yet the current technology is limited in resolution and dimensionality. Here, we introduce highly sensitive chemigenetic kinase activity biosensors that combine the genetically encodable self-labeling protein tag HaloTag7 with bright far-red-emitting synthetic fluorophores.

P6 is another one of the most popular rooftop bars in downtown Austin. What makes P6 so special is the history that comes with it. This place used to be a rooftop parking garage that was transformed and reinvented into an open space for open-air dining. Aside from delicious cocktails, the menu also features Mediterranean small plates. Some light food pairings to go with your cocktail are the roasted tomato hummus as well as rosemary scones that come with sherry tomato jam and parsley.