Samuel Wiafe on Muck Rack

Samuel Wiafe

As seen in: Modern Ghana, Nature, Wiley Online Library, Taylor & Francis Online, Applied and Environmental Soil Science, News Ghana, Daily Ghana
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Articles

Biallelic variants in RNU2-2 cause a remarkably frequent developmental and epileptic encephalopathy

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By Adam Jackson, Alexander Blakes, Bader Alhaddad, Olivia Henry, Elizabeth 'Ebbie' Wall, Ola A. Abdelhadi, Khadijah Bakur, Edward D Blair, Angela Brady, Helen K Brittain, Kate Chandler, Natasha Clarke, Irene Duba, Frances Elmslie, Jamie M. Ellingford, Lisa J. Ewans, Andrew Fennell, Simon Heller, Anna Hammarsjö, Nicole Lesko, Anna Lindstrand, Rebecca Macintosh, Sahar Mahmoud Mansour, Lara Menzies, Kay Metcalfe, Lina Nashef, Raymond T. O’Keefe, Elizabeth Palmer, Amitav Parida, Melody Redman, Alessandra Renieri, Chiara Fallerini, Caterina Rizzo, Rani Sachdev, Cas Simons, Sanjay M Sisodiya, Helen Stewart, Tommy Stödberg, Benito Banos-Pinero, Fulya Taylan, Huw Thomas Verified, Samuel Wiafe, Anna Wedell, Nicola Whiffin, Susan Walker, Rocio Rius, Ann Nordgren, Fowzan S. Alkuraya, Jenny Lord, Siddharth Banka, Angelica M. Delgado-Vega, Shakti Agrawal, Miriana Danelli, Nicholas Drinkall, Gabriella Gazdagh, Kristina Karrman, Usha Kini, Alison Milhench, Nadja Pekkola Pacheco, Katrina Prescott, Flavia Tinella, Jong Hee Chae
| Nature Verified
Abstract Neurodevelopmental disorders (NDDs) affect 2–4% of the population, are predominantly genetic and remain unsolved in ~50% of individuals. We show that rare biallelic variants in RNU2-2 are enriched and over-transmitted in individuals with unresolved NDDs. We define a recessive RNU2-2 syndrome, delineate its unique genetic architecture and show that it manifests clinically as a severe developmental and epileptic encephalopathy.
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Optimizing coagulation efficiency in surface water treatment using response surface method

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By Samuel Wiafe, Hanson Mensah Akkutteh
| Taylor & Francis Online
Abstract This study investigates the optimization of alum dosing in surface water treatment at Ghana’s Weija Water Treatment Plant using response surface methodology (RSM). By combining conventional jar tests, historical data (2002–2016) and 2018 seasonal experiments, the research evaluates the impact of raw water quality, especially turbidity, pH, color and polycyclic aromatic hydrocarbons (PAHs), on coagulation efficiency.
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Toxicological Impact of Heavy Metal Contamination in Vegetables on Human Health: A Case Study of Konongo, Ghana

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By Samuel Wiafe, William Adu Asamoah, Japhat Opoku Ofosu, Thomas Bandoh
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. References , , and . 2018. “Mercury Contamination in Nigerian Vegetables and Its Potential Health Risks.” Environmental Science and Pollution Research 25, no. 7: 12345–12357. , , and . 2023. “Health Impacts of Arsenic in Food Crops: A Critical Review.” Journal of Environmental Health 46, no. 1: 33–47. , and . 2015. “Methods for Sample Digestion in Trace Metal Analysis.” Journal of Food Composition and Analysis 21, no. 3: 192–200. 2017.
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