Sandanger TM

This study established the IINS by integrating systemic inflammatory, immune, and nutritional indicators, and further developed a postoperative survival prediction nomogram model for NSCLC combined with clinicopathological features. Based on multi-center retrospective cohorts and the NHANES external validation cohort, the IINS demonstrated stable cross-cohort performance in predicting OS and DFS.

CRAO is globally recognized as a severe retinal vascular condition, potentially leading to irreversible vision loss if not addressed promptly. Although the pathobiology of CRAO is multifactorial and its pathogenesis remains elusive, inflammation, abnormal lipid metabolism, and thrombosis are widely acknowledged as pivotal factors in its development. Recent studies have identified the NLR, SII, and MHR as innovative markers of inflammation, abnormal lipid metabolism and thrombosis.

1Medical Department, University Hospital, Qingdao Agriculture University, Qingdao, China 2Department of Obstetrics and Gynecology, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, China DOI 10.7717/peerj.17499 Academic Editor Vladimir Jurisic Subject Areas Oncology, Pathology Keywords High-grade squamous intraepithelial lesion (HSIL), Cervical...