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Sandile Cele

As seen in: Nature, Cell Host & Microbe, eLife
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Articles

Beta infection combined with Pfizer BNT162b2 vaccination leads to broadened neutralizing immunity against Omicron

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By Sandile Cele, Farina Karim, Khadija Shafaat Khan, Mallory Bernstein
| medRxiv
Sandile Cele, Mallory Bernstein, View ORCID ProfileFarina Karim, Khadija Khan, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Gila Lustig, Natasha Samsunder, Matilda Mazibuko, Shi-Hsia Hwa, Nithendra Manickchund, Anne von Gottberg, Nombulelo Magula, View ORCID ProfileRichard J. Lessells, View ORCID ProfileTulio de Oliveira, Salim S. Abdool Karim, Willem Hanekom, COMMIT-KZN Team, Bernadett I. Gosnell, View ORCID ProfileMahomed-Yunus S.
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Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant

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By Khadija Shafaat Khan, Farina Karim, Sandile Cele, James Emmanuel San
| medRxiv
View ORCID ProfileKhadija Khan, Farina Karim, Sandile Cele, James Emmanuel San, Gila Lustig, Houriiyah Tegally, Yuval Rosenberg, Mallory Bernstein, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Nokuthula Ngcobo, Matilda Mazibuko, Ntombifuthi Mthabela, Zoey Mhlane, Nikiwe Mbatha, Yoliswa Miya, Jennifer Giandhari, Yajna Ramphal, Taryn Naidoo, Nithendra Manickchund, Nombulelo Magula, Salim S.
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SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape

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By Sandile Cele, Farina Karim, Gila Lustig
| Cell Host & Microbe Verified
Highlights • An ancestral SARS-CoV-2 infection persisting over 6 months evolved neutralization escape • Evolved virus serological relationship is mapped to ancestral virus and key variants • Evolved virus shows greatest escape from Delta and least from Beta-elicited immunity • Evolved virus substantially but incompletely escapes BNT162b2 vaccine-elicited antibodies Summary properties of variants coming from these regions.
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