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Saniye Gül Kaya

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Articles

Condition-dependent amorphous protein agglomerates control cytoplasmic rheology

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By José L. Losa, François SIMON, Dmitrii Linnik, Saniye Gül Kaya, Marc Stuart, Artem Stetsenko, Rinse de Boer, Franz Y Ho, Danny Incarnato, Jan V. Stevens, Jan Van Eck, Marco W. Fraaije, Lucien E. Weiss, Sven van Teeffelen, Sanne Abeln, Albert Guskov, Siewert-Jan Marrink, Bert Poolman, Matthias Heinemann
| Cell Press Verified
Keywords cytoplasm protein agglomeration amino acid metabolism single-particle tracking intracellular diffusion Introduction The cytoplasm is a packed environment where, in bacteria, macromolecules such as proteins and RNA reach concentrations of ∼300 and ∼100 g/L, respectively, and volume fractions of up to 20%.1,2,3,4 This molecular crowding influences cytoplasmic rheology, i.e., how the cytoplasm flows and deforms.
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