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Sanjib Guha

As seen in: Nature, Odisha Bytes
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Articles

Large-scale single-molecule analysis of tau proteoforms

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By James H Joly, Vivekananda Budamagunta, Zhengjian Zhang, RAJAT BHATNAGAR, Jarrett D Egertson, Sanjib Guha, Kevin McVey, Nicholas Nelson, Rukshan T Perera, Steven Tan, Tuan Trinh, David Arnott, Joanna Lipka, Nikhil J. Pandya, Lionel Rougé, Timothy J Wendorff, Donald S. Kirkpatrick, Alexis Rohou, David Butler, Steven Lotz, Emily R. Sartori, Jessica E Schwarz, Kevin Chen, Ross Hartley, Kevin Jin, Denise Miller, Maureen Newman, Julia Robinson, Noah L. Steiner, Juanfeng Sun, Zhiqiang Wang, Sujal Patel, Sally Temple, Taylor Bertucci, Joel Blanchard, Andreas Hühmer, Parag Mallick, Brittany Nortman, Maryam Jouzi, Michael E. Flaster, Rob Grothe, Kota Kaneshige, Ana Forton, Phillip S. Brereton, Michael A. Darcy, Hamid R. Golnabi, Pierre F. Indermuhl, Christina E. Inman, Stanislav Katsyuk, Rajesh Kota, Bryant Lowry, Jonathan C. Menger, Adedeji Ogunyemi, Scott M. Tabakman, Lisen Wang, Sheri K. Wilcox, Gregory T. Kapp, Subramanian V. Sankar, Kara Juneau
| Nature Verified
Abstract Proteins exist as diverse proteoforms resulting from a combination of genetic variation, alternative splicing and post-translational modifications. Current methods struggle to capture this complexity at the single-molecule level. Here we introduce Iterative Mapping of proteoforms, a method that enables massively parallel interrogation of millions to billions of single-protein molecules through iterative probing with fluorescently labeled antibodies.
Open in Who Shared Issue with article?
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By Sanjib Guha
| Odisha Bytes Verified
Share New Delhi: The Congress Working Committee — the party’s top decision-making body — that met on Sunday to take a call on the future course of action, decided to continue with Sonia Gandhi as the president at least till the next election due in August-September. The CWC also decided that a ‘Chintan Shivir’ or brainstorming session will be conducted after the Parliament session ends on April 8.
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COVID-19: India Records Steep Decline In New Cases

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By Sanjib Guha
| Odisha Bytes Verified
New Delhi: India recorded a steep decline in COVID-19 cases in the country as it reported 5,921 fresh cases in the last 24 hours on Saturday, according to Union Health Ministry's updated data. The country registered 289 deaths in the last 24 hours, which took the toll to 5,14,878.
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