Skip To Main Content
Saovaros Svasti on Muck Rack

Saovaros Svasti

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Saovaros

Contact Saovaros, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Novel deferiprone resveratrol hybrid exhibits iron chelation and fetal hemoglobin induction in K562 cells supported by validated LC-MS/MS quantification

|
By Narisara Paradee, Muhammad Sadiq, Yongmin Ma, Khanita Nuamsee, Saovaros Svasti, Vudhiporn Limprasutr, Pipob Suwanchaikasem, Chaisak Chansriniyom, Seiichi Sakamoto, Varalee Yodsurang, Somdet Srichairatanakool, Pimpisid Koonyosying, Thararat Yimcharoen, Khin Khin Khaing
| Nature Verified
Abstract Multiple blood transfusions aim to improve anemia and maintain hemoglobin level in β-thalassemia patients; nonetheless, the consequent iron overloading raises serious complications. Nowadays, fetal hemoglobin (HbF) induction and iron chelation therapy are two strategic treatments for β-thalassemia aimed at ameliorating ineffective erythropoiesis and reducing complications from iron overload.
Open in Who Shared Issue with article?

Restoration of correct βIVS2-654-globin mRNA splicing and HbA production by engineered U7 snRNA in β-thalassaemia/HbE erythroid cells

|
By Tiwaporn Nualkaew, Natee Jearawiriyapaisarn, Suradej Hongeng, Saovaros Svasti
| Nature Verified
Abstract A cytosine to thymine mutation at nucleotide 654 of human β-globin intron 2 (βIVS2-654) is one of the most common mutations causing β-thalassaemia in Chinese and Southeast Asians. This mutation results in aberrant β-globin pre-mRNA splicing and prevents synthesis of β-globin protein.
Open in Who Shared Issue with article?
See all 2 articles