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Varalee Yodsurang on Muck Rack

Varalee Yodsurang

As seen in: Nature, PLOS
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Articles

Novel deferiprone resveratrol hybrid exhibits iron chelation and fetal hemoglobin induction in K562 cells supported by validated LC-MS/MS quantification

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By Narisara Paradee, Muhammad Sadiq, Yongmin Ma, Khanita Nuamsee, Saovaros Svasti, Vudhiporn Limprasutr, Pipob Suwanchaikasem, Chaisak Chansriniyom, Seiichi Sakamoto, Varalee Yodsurang, Somdet Srichairatanakool, Pimpisid Koonyosying, Thararat Yimcharoen, Khin Khin Khaing
| Nature Verified
Abstract Multiple blood transfusions aim to improve anemia and maintain hemoglobin level in β-thalassemia patients; nonetheless, the consequent iron overloading raises serious complications. Nowadays, fetal hemoglobin (HbF) induction and iron chelation therapy are two strategic treatments for β-thalassemia aimed at ameliorating ineffective erythropoiesis and reducing complications from iron overload.
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Gene-based therapy for the treatment of spinal muscular atrophy types 1 and 2 : a systematic review and meta-analysis - Gene Therapy

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By Varalee Yodsurang
| Nature Verified
Abstract Despite numerous studies identifying the advantages of therapies for spinal muscular atrophy (SMA), healthcare professionals encounter obstacles in determining the most effective treatment. This study aimed to investigate the effects of gene-based therapy for SMA. A systematic search was conducted from inception to May 2024 across databases, and all studies assessing the effects of gene-based therapy on patients with SMA types 1 and 2 were included.
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Triple-negative breast cancer influences a mixed M1/M2 macrophage phenotype associated with tumor aggressiveness

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By Rattana Saetung, Varalee Yodsurang, Chatchai Chaotham, Koramit Suppipat
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Abstract Triple-negative breast cancer (TNBC) is characterized by excessive accumulation of tumor-infiltrating immune cells, including tumor-associated macrophages (TAMs). TAMs consist of a heterogeneous population with high plasticity and are associated with tumor aggressiveness and poor prognosis. Moreover, breast cancer cells can secrete factors that influence TAM polarization.
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