Sara Lewis on Muck Rack

Sara Lewis

Boston
As seen in: CNN, Color Research & Application, HuffPost, Nature, The Guardian, USA Today, Wiley Online Library, TED, JSTOR Daily, MDPI and
once loved twitter, but I’ve now moved on. Come join me @Threads ✨💚 www.threads.net/@silentsparks #fireflies #SciComm #wonder
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Articles

High-resolution single-cell mapping of clonal hematopoiesis and structural variation in aplastic anemia

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By Masanori Yoshida, Sushree S. Sahoo, Paula Arnold, Carmelo Gurnari, Anaïs van Leeuwen, Limeng Pu, Ti-Cheng Chang, Rashid Mehmood, Nathan Gray, Michelle Boals, Sara Lewis, Lili Kotmayer, Swapna Thota, Wenchao Zhang, Yichao Li, Emily Walker, Christy W. LaFlamme, Heather C Mefford, Zachary Brady, Yash Shah, Miriam Erlacher, Brigitte Strahm, Ayami Yoshimi, Shinsuke Hirabayashi, Helen Reed, Akiko Shimamura, Guolian Kang, Xiang Chen, Jinghui Zhang, Charlotte M. Niemeyer, Joseph H. Oved, Timothy Olson, Ruben van Boxtel, Jaroslaw Maciejewski, Daria V. Babushok, Marcin Wlodarski, Markus J. van Roosmalen, Charnise Goodings, Lucca L. M. Derks, Cristyn N. Branstetter, Joshua Leow, Melanie R. Loyd, Granger Ridout, Rheanna G. Congdon
| Nature Verified
Abstract Aplastic anemia (AA) results from T-cell-mediated destruction of hematopoietic stem and progenitor cells (HSPCs), driving clonal hematopoiesis via loss of human leukocyte antigen (HLA) risk alleles (HLA loss-of-function mutations or uniparental disomy 6p, UPD6p), paroxysmal nocturnal hemoglobinuria and clonal hematopoiesis of indeterminate potential (CHIP) mutations.
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Expanding the Phenotypic Spectrum of the Recurrent De Novo FBXO31 p.Asp334Asn Variant: Evidence for a Novel Neurodevelopmental Disorder (Kruer Syndrome)

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By Sara Lewis, Maureen Galindo, Carolina I. Galaz-Montoya
| Wiley Online Library Verified
Conflicts of Interest I.M.W. is an employee of and may own stock in GeneDx. The other authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Peer Review For transparency, the peer review documents associated with this article are available at https://doi.org/10.1111/cge.70166.
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A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies

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By Brian L. Gudenas, Shiekh Tanveer Ahmad, Bernhard Englinger, Anthony Liu, Miao Zhao, Leena Paul, Jennifer Hadley, Yiran Li, Melissa Batts, Priya MIttal, Priya Mittal, Stephanie Wu Verified, Sara Lewis, Katie Han, Taha Soliman, Hong Lin, David Meredith Verified, Elke Pfaff, Johannes Gojo, Jennifer Cotter, Paul Klimo, Frederick A. Boop, Amar Gajjar, Giles W Robinson, Gabriela Rosén, Sanda Alexandrescu, Brent A. Orr, Fredrik J. Swartling, Mariella G. Filbin, Paul A. Northcott
| Cell Press Verified
Human tumor tissue collection and dissociation To extract intact, single nuclei from frozen tissues for snRNA-seq, snap-frozen or OCT-embedded tumor tissue was disaggregated on ice in 1 mL 0.49% CHAPS detergent-based nuclear extraction buffer that was previously optimized for the lysis of brain tissue,86 aided by mild chopping using sterile scissors.
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