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Savina Abraham Pol on Muck Rack

Savina Abraham Pol

As seen in: BioRxiv
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Articles

Induced degradation of SNAP-fusion proteins

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By Jack Barr, Gina Simon, Savina Abraham Pol, Sara Liljenberg
| BioRxiv
Abstract Self-labeling protein tags are an efficient means to visualize, manipulate, and isolate engineered fusion proteins with suitable chemical probes. The SNAP-tag, which covalently conjugates to benzyl-guanine and -chloropyrimidine derivatives is used extensively in fluorescence microscopy, given the availability of suitable SNAP-ligand-based probes. Here, we extend the applicability of the SNAP-tag to targeted protein degradation.
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