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Sean Bennett on Muck Rack

Sean Bennett

As seen in: Illumination, Medium, The Startup, PLOS Biology, New Zealand Herald, BioRxiv, Cell Press, Refinery29, Journal of Nursing Education, eLife and
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Articles

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

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By Danielle Hamm, Ellen Paatela, Sean Bennett, Chao-Jen Wong
| PLOS Biology Verified
Supporting information (A) Immunoblot analysis of DUX4 targets H3.X/Y/Z, MHC-I, iProteasome subunits PSMB9 and PSMB10, and localization controls GAPDH (cytoplasmic) and Histone H3 (nuclear) after nuclear and cytoplasmic fractionation. MB135iDUX4 myoblasts were treated with or without DOX for 4 hours, and 24 hours later stimulated with or without IFNγ 16 hours; harvested cells 44 hours post-DOX treatment (DOX pulse, 44 hours).
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The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

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By Danielle Hamm, Ellen Paatela, Sean Bennett, Chao-Jen Wong
| tinyurl.com
Citation: Hamm DC, Paatela EM, Bennett SR, Wong C-J, Campbell AE, Wladyka CL, et al. (2023) The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs. PLoS Biol 21(9): e3002317.
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Writing The World Better

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By Sean Bennett
| Medium
By Sean Bennett One keystroke at a time Laying in bed, staring up at the shadow-soaked ceiling, I think the kind of deep thoughts that always accompany a clear, cold night. What is the world coming too? What is my place in it? Where are we headed? How can we be better? The world seems broken and fractured, these days. There's barely time to recover from one crisis...
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