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Sean Grambart on Muck Rack

Sean Grambart

As seen in: ScienceDirect, The Clinical Advisor
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Articles

Hepatocellular carcinoma epi-immunotherapy with polyion complex micelles co-delivering HDAC8 inhibitor and PD-L1 siRNA

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By J.M. Llovet, Sean Grambart, John Bennett, Yonglan Yang
| ScienceDirect Verified
Hepatocellular carcinoma (HCC) is the most common primary liver malignant disease and the fourth most common tumor worldwide [1], [2], [3]. Besides, the prognosis of HCC is very poor and the 5-year relative survival rate is approximately 12 % [4], [5], [6]. Notably, HCC as a noninflamed tumor infiltrated with extensive immunosuppressive cells and heavily lacked cytotoxic T lymphocytes, which limited the efficacy of immune checkpoint inhibitors (ICIs) in HCC patients [1], [4], [7].
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Treating patients with a fracture: Engage an expert

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By Sean Grambart
| The Clinical Advisor Verified
Partnership is imperative, especially in a field like ours. As healthcare professionals, we work hard to bring the best care we can to our patients, but we are frequently faced with an injury, condition, or ailment that is outside of our expertise. This is when collaboration becomes even more essential.
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