Sébastien Barbarot
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CO119 NATURAL HISTORY, MANAGEMENT, AND BURDEN OF DISEASE IN ADULTS WITH NF1 AND SYMPTOMATIC INOPERABLE PLEXIFORM NEUROFIBROMA IN FRANCE
1Assistance Publique - Hôpitaux de Paris, Department of Dermatology, National Referral Center for Neurofibromatoses, Henri Mondor Hospital, Créteil, France 2University Hospital of Nantes, Dermatology Department, Nantes, France 3Alexion, AstraZeneca Rare Disease, Global HEOR, Boston, MA, USA 4Alexion, AstraZeneca Rare Disease, Medical Metabolics, Paris, France 5IQVIA, Real World Solutions, Courbevoie, France 6Centre Léon Bérard, Department of Dermatology, Lyon, France
Trametinib for multiple non-ossifying fibromas due to KRAS mosaic mutations: two case reports
Abstract KRAS mosaic activating variants are the main cause of non-ossifying fibromas (NOFs), the most common benign lesion of the growing skeleton. Multifocal NOFs cause bone fragility, and no specific treatment is currently available.
Public‐health implications of market drug withdrawals: A focus on antifungals for tinea capitis
Public-health implications of market drug withdrawals: A focus on antifungals for tinea capitis On behalf of Centre of Evidence of the French Society of Dermatology, Paris, France.
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