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Semel Institue

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Articles

Neuronal protein interaction networks in autism spectrum disorder

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By Daniel H Geschwind, Semel Institue, Lucy K. Bicks, Katherine Wade Eyring
| Cell Press Verified
Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Department of Psychiatry and Biobehavioral Sciences, Semel Institue, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Department of Human Genetics, David Geffen School of Medicine,...
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Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility - Nature Neuroscience

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By Johns Hopkins, Semel Institue
| Nature Verified
Abstract Gene networks have yielded numerous neurobiological insights, yet an integrated view across brain regions is lacking. We leverage RNA sequencing in 864 samples representing 12 brain regions to robustly identify 12 brain-wide, 50 cross-regional and 114 region-specific coexpression modules.
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